Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively

Logo poskytovatele
Logo poskytovatele
Logo poskytovatele

Varování

Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
Autoři

MIKALOVÁ Lenka STROUHAL Michal OPPELT Jan GRANGE Philippe Alain JANIER Michel BENHADDOU Nadjet DUPIN Nicolas ŠMAJS David

Rok publikování 2017
Druh Článek v odborném periodiku
Časopis / Zdroj PLoS neglected tropical diseases
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005434
Doi http://dx.doi.org/10.1371/journal.pntd.0005434
Obor Epidemiologie, infekční nemoci a klinická imunologie
Klíčová slova Treponema pallidum
Popis The TEN 11q/j isolate was characterized using nested PCR followed by Sanger sequencing and/or direct Illumina sequencing. Altogether, 44 chromosomal regions were analyzed. Overall, the 11q/j isolate clustered with TEN strains Bosnia A and Iraq B as expected from previous TEN classification of the 11q/j isolate. However, the 11q/j sequence in a 505 bp-long region at the TP0488 locus was similar to Treponema pallidum subsp. pallidum (TPA) strains, but not to TEN Bosnia A and Iraq B sequences, suggesting a recombination event at this locus. Similarly, the 11q/j sequence in a 613 bp-long region at the TP0548 locus was similar to Treponema pallidum subsp. pertenue (TPE) strains, but not to TEN sequences.
Související projekty:

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.