Termination of Shoot Gravitropic Responses by Auxin Feedback on PIN3 Polarity

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Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.
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RAKUSOVÁ Hana ABBAS Mohamad HAN Huibin SONG Siyuan ROBERT BOISIVON Helene FRIML Jiří

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Current Biology
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
www http://www.cell.com/action/showImagesData?pii=S0960-9822%2816%2931012-0
Doi http://dx.doi.org/10.1016/j.cub.2016.08.067
Obor Genetika a molekulární biologie
Klíčová slova gravitropism; Arabidopsis; hypocotyl; auxin; auxin transport; auxin feedback; PIN polarity
Popis Plants adjust their growth according to gravity. Gravitropism involves gravity perception, signal transduction, and asymmetric growth response, with organ bending as a consequence [1]. Asymmetric growth results from the asymmetric distribution of the plant-specific signaling molecule auxin [2] that is generated by lateral transport, mediated in the hypocotyl predominantly by the auxin transporter PIN-FORMED3 (PIN3) [3, 4, 5]. Gravity stimulation polarizes PIN3 to the bottom sides of endodermal cells, correlating with increased auxin accumulation in adjacent tissues at the lower side of the stimulated organ, where auxin induces cell elongation and, hence, organ bending. A curvature response allows the hypocotyl to resume straight growth at a defined angle [6], implying that at some point auxin symmetry is restored to prevent overbending. Here, we present initial insights into cellular and molecular mechanisms that lead to the termination of the tropic response. We identified an auxin feedback on PIN3 polarization as underlying mechanism that restores symmetry of the PIN3-dependent auxin flow. Thus, two mechanistically distinct PIN3 polarization events redirect auxin fluxes at different time points of the gravity response: first, gravity-mediated redirection of PIN3-mediated auxin flow toward the lower hypocotyl side, where auxin gradually accumulates and promotes growth, and later PIN3 polarization to the opposite cell side, depleting this auxin maximum to end the bending. Accordingly, genetic or pharmacological interference with the late PIN3 polarization prevents termination of the response and leads to hypocotyl overbending. This observation reveals a role of auxin feedback on PIN polarity in the termination of the tropic response.
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