Advances in Xmipp for Cryo–Electron Microscopy: From Xmipp to Scipion

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Authors

STŘELÁK David JIMÉNEZ-MORENO Amaya VILAS José RAMÍREZ-APORTELA Erney SÁNCHEZ-GARCÍA Ruben MALUENDA David VARGAS Javier HERREROS David FERNÁNDEZ-GIMÉNEZ Estrella DE ISIDRO-GÓMEZ Federico HORÁČEK Jan MYŠKA David HORÁČEK Martin CONESA Pablo FONSECA-REYNA Yunior JIMÉNEZ Jorge MARTÍNEZ Marta HARASTANI Mohamad JONIĆ Slavica FILIPOVIČ Jiří MARABINI Roberto CARAZO José SORZANO Carlos

Year of publication 2021
Type Article in Periodical
Magazine / Source Molecules
MU Faculty or unit

Faculty of Informatics

Citation
Web https://www.mdpi.com/1420-3049/26/20/6224
Doi http://dx.doi.org/10.3390/molecules26206224
Keywords Xmipp; Cryo-EM; Scipion; single-particle analysis
Description Xmipp is an open-source software package consisting of multiple programs for processing data originating from electron microscopy and electron tomography, designed and managed by the Biocomputing Unit of the Spanish National Center for Biotechnology, although with contributions from many other developers over the world. During its 25 years of existence, Xmipp underwent multiple changes and updates. While there were many publications related to new programs and functionality added to Xmipp, there is no single publication on the Xmipp as a package since 2013. In this article, we give an overview of the changes and new work since 2013, describe technologies and techniques used during the development, and take a peek at the future of the package.
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