Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature

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Authors

ŘÍČNÁ Dita LENGEROVÁ Martina PALACKOVÁ Martina HADRABOVÁ Markéta KOCMANOVÁ Iva WEINBERGEROVÁ Barbora PAVLOVSKÝ Zdeněk VOLFOVÁ Pavlína BOUCHNEROVÁ Jana MAYER Jiří RÁČIL Zdeněk

Year of publication 2016
Type Article in Periodical
Magazine / Source Mycoses
MU Faculty or unit

Faculty of Medicine

Citation
Web http://dx.doi.org/10.1111/myc.12421
Doi http://dx.doi.org/10.1111/myc.12421
Field Oncology and hematology
Keywords Fusariosis; Fusarium proliferatum; PCR diagnostics; Real-time PCR
Attached files
Description Disseminated fusariosis is a life-threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.
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