Project information
Vliv terapeutické inhibice BCR signalizace na genovou expresi u B buněčných malignit a její prognostický a prediktivní význam
- Project Identification
- 16-29622A (kod CEP: NV16-29622A)
- Project Period
- 4/2016 - 12/2019
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- Ministry of Health Research Programme 2015 - 2022
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
-
University Hospital Brno-Bohunice
- Responsible person prof. MUDr. Mgr. Marek Mráz, Ph.D.
Vliv terapeutické inhibice BCR signalizace na genovou expresi u B buněčných malignit a její prognostický a prediktivní význam
Publications
Total number of publications: 35
2018
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miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels
Blood, year: 2018, volume: 132, edition: 22, DOI
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MYC-mediated downregulation of miR-150 contributes to the transformation of follicular lymphoma by upregulating FOXP1 levels
Year: 2018, type: Conference abstract
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MYC-mediated downregulation of miR-150 contributes to the transformation of follicular lymphoma to DLBCL by upregulating FOXP1 levels
Year: 2018, type: Conference abstract
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Rituximab primarily targets an intra-clonal BCR signaling proficient CLL subpopulation characterized by high CD20 levels
Leukemia, year: 2018, volume: 32, edition: 9, DOI
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The expression of T-cell specific microRNA associates with the transformation of indolent follicular lymphoma to agressive lymphomas
Year: 2018, type: Conference abstract
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The Light Chain IgLV3-21 Defines a New Poor Prognostic Subgroup in Chronic Lymphocytic Leukemia: Results of a Multicenter Study
Clinical cancer research, year: 2018, volume: 24, edition: 20, DOI
2017
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BCR signalling proficient chronic lymphocytic leukaemia cells are prone to rituximab mediated elimination in vivo.
Year: 2017, type: Conference abstract
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Buněčná biologie folikulárního lymfomu
Folikulární lymfom, edition: První vyd., year: 2017, number of pages: 21 s.
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Differential expression of microRNAs in transformation of follicular lymphoma to diffuse large B cell lymphoma
Year: 2017, type: Conference abstract
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Down-regulation of miR-150 and up-regulation of its target FOXP1 is associated with transformation of follicular lymphoma.
Year: 2017, type: Conference abstract